Description

Benzene, 1-(Bromomethyl)-3-Chloro-5-Nitro- is a high-purity, multi-functional halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of reactive bromomethyl, chloro, and nitro groups on the aromatic ring, enabling precise and sequential functionalization. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable, high-quality intermediate for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the nitro and halogen substituents contribute to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in catalysis and material science.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of complex azo dyes and other colored compounds.
• Polymer Modification: Employed to introduce functional groups into polymer chains, altering physical properties for advanced material applications.
• Cross-coupling Reactions: The bromomethyl group makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Chemical Research: A versatile reagent for academic and industrial R&D focused on novel heterocyclic and aromatic compound synthesis.

Basic Information

Product Name	Benzene, 1-(Bromomethyl)-3-Chloro-5-Nitro-
CAS No.	865624-17-5
Molecular Formula	C7H5BrClNO2
Molecular Weight	250.48 g/mol
Synonyms	1-(Bromomethyl)-3-chloro-5-nitrobenzene; 3-Chloro-5-nitrobenzyl bromide; (3-Chloro-5-nitrophenyl)methyl bromide; α-Bromo-3-chloro-5-nitrotoluene; NSC 403120; Benzyl bromide, 3-chloro-5-nitro-; 3-Chloro-5-nitrobenzylbromide; 3-Chloro-5-nitrobenzyl bromide
EINECS	Contact for details

Quality Control

Every batch of Benzene, 1-(Bromomethyl)-3-Chloro-5-Nitro- undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of GMP and ISO standards for chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging. Store separately from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Related Substances (HPLC)	Total impurities < 2.0%
Solubility	Soluble in common organic solvents (e.g., DMF, THF, Acetone)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.