Description

Chloro(Mesitylene)[(1S,2S)-(+)-2-Amino-1,2-Diphenylethyl(Methylsulfonylamido)]Ruthenium(II) RuCl(Mesitylene)[(S,S)-MsDPEN] is a highly specialized, chiral ruthenium complex that serves as a premier asymmetric hydrogenation catalyst. Its value lies in enabling the production of enantiomerically pure intermediates, which are critical for the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high selectivity and efficiency in catalytic transformations.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and olefins in pharmaceutical intermediate synthesis.
• Pharmaceutical API Manufacturing: Key for producing chiral amines and amino acid derivatives used in drug development.
• Agrochemical Synthesis: Used in the creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Enables high-value, chiral transformations in custom synthesis and specialty chemical manufacturing.
• Academic & Industrial Research: A valuable tool for methodology development in organic synthesis and catalysis studies.
• Process Chemistry Optimization: Employed for scaling up efficient and selective catalytic processes from lab to pilot plant.

Basic Information

Item	Details
Product Name	Chloro(Mesitylene)[(1S,2S)-(+)-2-Amino-1,2-Diphenylethyl(Methylsulfonylamido)]Ruthenium(II)
CAS No.	865488-44-4
Molecular Formula	C24H29ClN2O2RuS
Molecular Weight	546.08 g/mol
Synonyms	RuCl(Mesitylene)[(S,S)-MsDPEN]; (S,S)-RuCl(mesitylene)(MsDPEN); [RuCl((S,S)-MsDPEN)(mesitylene)]; (1S,2S)-N-(Methylsulfonyl)-1,2-diphenylethylenediamine (mesitylene)ruthenium(II) chloride; Noyori-Ikariya Catalyst Derivative; Chiral Ruthenium-Diamine Complex; Asymmetric Hydrogenation Catalyst 865488-44-4
EINECS	Contact for details

Quality Control

Every batch of our chiral ruthenium catalyst is manufactured and tested under strict quality management systems to ensure high purity and catalytic performance. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as chiral purity, metal content, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent decomposition. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or ambient light should be avoided.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Ruthenium Content	Contact for details
Solubility	Soluble in dichloromethane, toluene, THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.