Description

1-(5-Chloro-4-Fluoro-2-Hydroxy-Phenyl)-Ethanone is a high-purity, halogenated aromatic ketone building block of significant importance in advanced organic synthesis. Its unique structure, featuring chloro, fluoro, and phenolic hydroxyl substituents, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated phenolic scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where its halogen atoms contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a building block for developing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical reactions, catalysis, and the development of novel heterocyclic compounds.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex halogenated dyes and functional pigments.

Basic Information

Product Name	1-(5-Chloro-4-Fluoro-2-Hydroxy-Phenyl)-Ethanone
CAS No.	865451-01-0
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	5'-Chloro-4'-fluoro-2'-hydroxyacetophenone; 1-(5-Chloro-4-fluoro-2-hydroxyphenyl)ethan-1-one; 2-Acetyl-4-chloro-5-fluorophenol; 4-Chloro-5-fluoro-2-hydroxyacetophenone; 2-Hydroxy-5-chloro-4-fluoroacetophenone; 5-Chloro-4-fluoro-2-hydroxyacetophenone; 1-Acetyl-5-chloro-4-fluoro-2-hydroxybenzene
EINECS	Contact for details

Quality Control

Our 1-(5-Chloro-4-Fluoro-2-Hydroxy-Phenyl)-Ethanone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.