Description

1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylicacid,5-Hydroxy-3-Methyl-,1,1-Dimethylethylester is a high-purity, advanced pharmaceutical intermediate with the CAS number 864775-98-4. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, where its specific heterocyclic structure enables precise molecular design.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for constructing complex molecules with targeted biological activity.
• Biochemical Research: Used in academic and industrial R&D for studying enzyme inhibition and receptor binding mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylicacid,5-Hydroxy-3-Methyl-,1,1-Dimethylethylester
CAS No.	864775-98-4
Molecular Formula	C13H15N3O3
Molecular Weight	261.28 g/mol
Synonyms	5-Hydroxy-3-methyl-1H-pyrazolo[3,4-b]pyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 5-hydroxy-3-methyl-1H-pyrazolo[3,4-b]pyridine-1-carboxylate; 1-(tert-Butoxycarbonyl)-5-hydroxy-3-methyl-1H-pyrazolo[3,4-b]pyridine; 1-Boc-5-hydroxy-3-methyl-1H-pyrazolo[3,4-b]pyridine; 864775-98-4; 5-Hydroxy-3-methyl-1-(tert-butoxycarbonyl)-1H-pyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylicacid,5-Hydroxy-3-Methyl-,1,1-Dimethylethylester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specified parameters. We support development and commercial projects with material suitable for research use through to cGMP-grade manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.