Description

3-Iodo-1-Methyl-7-Nitro-1H-Indazole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceutical agents and agrochemicals, enabling critical structural modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of targeted small molecule drugs, particularly in kinase inhibitor research.
• Agrochemical Research: Used in the development of new generation herbicides and pesticides with specific modes of action.
• Chemical Biology Probe: Acts as a versatile building block for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Employed in the synthesis of specialized organic electronic materials and photoactive compounds.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Library Synthesis for HTS: A valuable input for generating diverse compound libraries for high-throughput screening (HTS) in drug discovery.

Basic Information

Product Name	3-Iodo-1-Methyl-7-Nitro-1H-Indazole
CAS No.	864724-65-2
Molecular Formula	C8H6IN3O2
Molecular Weight	303.06 g/mol
Synonyms	1-Methyl-3-iodo-7-nitro-1H-indazole; 7-Nitro-1-methyl-3-iodo-1H-indazole; 3-Iodo-1-methyl-7-nitroindazole; 864724-65-2; 1H-Indazole, 3-iodo-1-methyl-7-nitro-
EINECS	Contact for details

Quality Control

Our 3-Iodo-1-Methyl-7-Nitro-1H-Indazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.