Description

Jwh 251 4-Methylphenyl Isomer CAS NO 864445-41-0 is a synthetic cannabinoid receptor agonist research chemical, specifically an isomer of the JWH-251 series. This compound is of significant interest for advanced pharmaceutical research and preclinical studies targeting the endocannabinoid system. It is primarily utilized by contract research organizations (CROs), academic institutions, and pharmaceutical R&D departments for biochemical and pharmacological investigation.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies of cannabinoid receptor (CB1/CB2) binding affinity and functional activity.
• Biochemical Assay Development: Serves as a key ligand in the development and validation of high-throughput screening (HTS) assays for drug discovery.
• Metabolic Pathway Studies: Employed in in vitro and in vivo studies to understand the metabolism and pharmacokinetics of synthetic cannabinoids.
• Analytical Reference Standard: Provides a high-purity benchmark for the identification and quantification of related compounds in forensic and regulatory analysis.
• Structure-Activity Relationship (SAR) Studies: Critical for medicinal chemistry programs aiming to design novel therapeutic agents with modified receptor selectivity and potency.

Basic Information

Product Name	Jwh 251 4-Methylphenyl Isomer
CAS No.	864445-41-0
Molecular Formula	C24H23NO
Molecular Weight	341.45 g/mol
Synonyms	1-Pentyl-3-(4-methyl-1-naphthoyl)indole; JWH-251 4-Methyl Isomer; 4-Methyl-JWH-251; 1-Pentyl-1H-indol-3-yl-(4-methylnaphthalen-1-yl)methanone; (1-Pentylindol-3-yl)-4-methyl-1-naphthylmethanone; JWH 251 Methylphenyl Isomer; Naphthalen-1-yl(1-pentyl-1H-indol-3-yl)methanone, 4-methyl-
EINECS	Contact for details

Quality Control

Our Jwh 251 4-Methylphenyl Isomer is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization using advanced techniques including HPLC, GC-MS, NMR, and IR spectroscopy to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to ISO 9001 guidelines, ensuring reliable and traceable material for your research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light tan crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.