Description

6-Bromo-2,4-Dichloro-8-Methoxyquinazoline is a high-purity, multi-halogenated quinazoline derivative, a crucial advanced intermediate in modern synthetic chemistry. Its value lies in its versatile reactivity, serving as a key building block for constructing complex heterocyclic scaffolds with targeted biological activity. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel kinase inhibitors, anticancer agents, and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a building block for creating organic electronic materials, such as charge-transport layers or luminescent compounds.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes and activity-based protein profiling (ABPP) reagents to study enzyme function.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) exploring new chemical space and structure-activity relationships (SAR).
• Custom Synthesis: A starting material for the contract manufacturing of bespoke, high-value compounds for client-specific applications.

Basic Information

Product Name	6-Bromo-2,4-Dichloro-8-Methoxyquinazoline
CAS No.	864292-36-4
Molecular Formula	C9H5BrCl2N2O
Molecular Weight	308.96 g/mol
Synonyms	8-Methoxy-6-bromo-2,4-dichloroquinazoline; 2,4-Dichloro-6-bromo-8-methoxyquinazoline; 6-Bromo-2,4-dichloro-8-methoxy-quinazoline; Quinazoline, 6-bromo-2,4-dichloro-8-methoxy-; BRD-K94237520
EINECS	Contact for details

Quality Control

Our 6-Bromo-2,4-Dichloro-8-Methoxyquinazoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring material that meets stringent internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.