Description

8-Bromo-2,4-Dichloro-6-Fluoroquinazoline is a high-value, multi-halogenated quinazoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its unique halogen substitution pattern makes it a versatile and reactive building block for constructing complex heterocyclic scaffolds. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small-molecule drug candidates, leveraging the quinazoline core's bioactivity.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the halogenated quinazoline structure can confer specific biological activity.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to the reactivity of its bromo and chloro substituents.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and the exploration of new chemical space in heterocyclic chemistry.

Basic Information

Product Name	8-Bromo-2,4-Dichloro-6-Fluoroquinazoline
CAS No.	864292-32-0
Molecular Formula	C8H2BrCl2FN2
Molecular Weight	309.92 g/mol
Synonyms	2,4-Dichloro-8-bromo-6-fluoroquinazoline; 6-Fluoro-8-bromo-2,4-dichloroquinazoline; 8-Bromo-2,4-dichloro-6-fluoro-quinazoline; Quinazoline, 8-bromo-2,4-dichloro-6-fluoro-; BDFQ
EINECS	Contact for details

Quality Control

Every batch of 8-Bromo-2,4-Dichloro-6-Fluoroquinazoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.