Description

2,4-Dichloro-6-(Trifluoromethyl)-Quinazoline is a high-value, multi-functional halogenated quinazoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring reactive chlorine atoms and a stable trifluoromethyl group, makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including potential drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinazoline-based drug candidates, including kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and pesticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the creation of specialty chemicals, organic electronic materials, and advanced polymers.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling and modifying biomolecules in probe development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for process development and scale-up projects.

Basic Information

Product Name	2,4-Dichloro-6-(Trifluoromethyl)-Quinazoline
CAS No.	864291-30-5
Molecular Formula	C9H3Cl2F3N2
Molecular Weight	267.04 g/mol
Synonyms	6-(Trifluoromethyl)-2,4-dichloroquinazoline; 2,4-Dichloro-6-(trifluoromethyl)quinazoline; Quinazoline, 2,4-dichloro-6-(trifluoromethyl)-; 2,4-Dichloro-6-trifluoromethylquinazoline
EINECS	Contact for details

Quality Control

Every batch of 2,4-Dichloro-6-(Trifluoromethyl)-Quinazoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.