Description

2,3-Difluoro-4'-Methyl-1,1'-Biphenyl is a high-purity fluorinated biphenyl derivative, a critical building block in advanced organic synthesis. Its value lies in its unique molecular architecture, which serves as a versatile scaffold for constructing complex molecules in pharmaceutical and materials science research. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and liquid crystal industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a core structural unit in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials or host materials in OLED device fabrication.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create more complex biaryl systems.
• Material Science Research: Employed in the development of organic semiconductors and other functional organic materials.

Basic Information

Product Name	2,3-Difluoro-4'-Methyl-1,1'-Biphenyl
CAS No.	864059-66-5
Molecular Formula	C₁₃H₁₀F₂
Molecular Weight	204.22 g/mol
Synonyms	2,3-Difluoro-4'-methylbiphenyl; 4'-Methyl-2,3-difluorobiphenyl; 1,1'-Biphenyl, 2,3-difluoro-4'-methyl-; [1,1'-Biphenyl]-2,3-difluoro-4'-methyl; 2,3-Difluoro-4'-methyl-1,1'-biphenyl
EINECS	Contact for details

Quality Control

Every batch of 2,3-Difluoro-4'-Methyl-1,1'-Biphenyl is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.