Description

Carbonylchlorohydrido[6-(Di-T-Butylphosphinomethyl)-2-(N,n-Diethylaminomethyl)Pyridine]Ruthenium(Ii), Min. 98% is a highly specialized organometallic complex, widely recognized as a key precursor to the Milstein catalyst. This compound is critical for enabling efficient and selective hydrogenation, dehydrogenation, and hydrogen transfer reactions under mild conditions. It is an essential reagent for R&D chemists and process engineers in pharmaceutical synthesis, fine chemical manufacturing, and advanced materials research, where precise catalytic activity is paramount.

Application

• Homogeneous Catalysis Research: Serves as the direct precursor for generating the active Milstein catalyst (a PNN pincer complex) for studying novel reaction mechanisms.
• Pharmaceutical Intermediate Synthesis: Enables key hydrogenation and acceptorless dehydrogenation steps in the production of complex drug molecules and active pharmaceutical ingredients (APIs).
• Fine Chemical Production: Used in the synthesis of flavors, fragrances, and specialty agrochemicals where selective bond activation is required.
• Hydrogen Storage & Transfer Reactions: Facilitates research into hydrogenation of CO₂, esters, and amides, as well as methanol reforming for energy applications.
• Ligand & Catalyst Development: A valuable starting material for synthesizing new ruthenium complexes with modified PNN pincer ligands for catalytic testing.
• Academic & Industrial R&D: A standard reagent in laboratories developing sustainable and atom-economical catalytic processes.

Basic Information

Product Name	Carbonylchlorohydrido[6-(Di-T-Butylphosphinomethyl)-2-(N,n-Diethylaminomethyl)Pyridine]Ruthenium(Ii), Min. 98% (Milstein Catalyst Precursor)
CAS No.	863971-62-4
Molecular Formula	C₂₂H₄₁ClN₂OPRu
Molecular Weight	515.07 g/mol
Synonyms	Milstein Catalyst Precursor; Ru-MACHO Precursor; Carbonylchlorohydrido(tri-tert-butylphosphinomethylamine)ruthenium(II); [RuHCl(CO)(PNN)]; PNN Pincer Ruthenium Complex Precursor; (6-(Di-tert-butylphosphinomethyl)-2-(N,N-diethylaminomethyl)pyridine)carbonylchlorohydridoruthenium(II); Ruthenium(II) carbonyl chloride hydride (PNN ligand) complex
EINECS	Contact for details

Quality Control

Every batch of our Milstein Catalyst Precursor is produced and controlled under stringent quality management protocols. We guarantee a minimum purity of 98%, verified by advanced analytical techniques including NMR and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and residual solvent content is provided with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to light and oxygen, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	Min. 98.0%
Solvent Residue (GC)	Meet ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.