Description

6-(Benzyloxy)-4-Chloroquinoline CAS NO 863786-01-0 is a high-purity, functionalized quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a benzyl-protected oxygen and a reactive chlorine substituent, makes it a versatile building block for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in medicinal chemistry, particularly for the synthesis of novel drug candidates and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential therapeutic agents, including kinase inhibitors and other biologically active quinoline-based molecules.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the quinoline scaffold's bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of advanced organic electronic materials and specialty polymers.
• Chemical Synthesis: Employed as a versatile building block for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitutions to introduce complex functionalities.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies and the exploration of new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	6-(Benzyloxy)-4-Chloroquinoline
CAS No.	863786-01-0
Molecular Formula	C₁₆H₁₂ClNO
Molecular Weight	269.73 g/mol
Synonyms	4-Chloro-6-(phenylmethoxy)quinoline; 4-Chloro-6-benzyloxyquinoline; 6-Benzyloxy-4-chloroquinoline; Quinoline, 4-chloro-6-(phenylmethoxy)-; 863786-01-0; 6-O-Benzyl-4-chloroquinoline
EINECS	Contact for details

Quality Control

Our 6-(Benzyloxy)-4-Chloroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.