Description

4-Chloro-6,7-Difluoroquinoline is a high-purity fluorinated quinoline derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals, where its unique halogenated structure enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in developing kinase inhibitors, antibacterial agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to construct advanced fungicides, herbicides, and pesticides, leveraging the quinoline core for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as charge-transport layers or light-emitting components, due to its conjugated aromatic system.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new organic reactions, catalytic processes, and the development of complex molecular architectures.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for metal-organic frameworks (MOFs) or catalysts for asymmetric synthesis.

Basic Information

Product Name	4-Chloro-6,7-Difluoroquinoline
CAS No.	863785-94-8
Molecular Formula	C9H4ClF2N
Molecular Weight	199.59 g/mol
Synonyms	6,7-Difluoro-4-chloroquinoline; 4-Chloro-6,7-difluoroquinoline; Quinoline, 4-chloro-6,7-difluoro-; 863785-94-8; 4-Chloro-6,7-difluoro-quinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-6,7-Difluoroquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.