Description

4-Methyl-1,5-dioxo-2,3,4,5-tetrahydropyrrolo[1,2-a]quinazoline-3a(1H)-carboxylic acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific biological pathways. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially in oncology and neurology research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing novel molecular scaffolds with potential biological activity.
• Research & Development (R&D): Serves as a standard or starting material in academic and industrial laboratories for method development and biological screening.
• Process Chemistry Optimization: Employed in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial production.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-Methyl-1,5-dioxo-2,3,4,5-tetrahydropyrrolo[1,2-a]quinazoline-3a(1H)-carboxylic acid
CAS No.	863763-60-4
Molecular Formula	C14H12N2O4
Molecular Weight	272.26 g/mol
Synonyms	4-Methyl-1,5-dioxo-2,3,4,5-tetrahydro-1H-pyrrolo[1,2-a]quinazoline-3a-carboxylic acid; 3a-Carboxy-4-methyl-2,3,4,5-tetrahydro-1H-pyrrolo[1,2-a]quinazoline-1,5-dione; Pyrroloquinazoline-dione carboxylic acid derivative; CAS 863763-60-4; 4-Methyl-1,5-dioxo-2,3,4,5-tetrahydro-pyrrolo[1,2-a]quinazoline-3a-carboxylic acid; 1H-Pyrrolo[1,2-a]quinazoline-3a(1H)-carboxylic acid, 2,3,4,5-tetrahydro-4-methyl-1,5-dioxo-
EINECS	Contact for details

Quality Control

Our production of 4-Methyl-1,5-dioxo-2,3,4,5-tetrahydropyrrolo[1,2-a]quinazoline-3a(1H)-carboxylic acid adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with exacting customer specifications and internal standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and consistency for your critical R&D and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.