Description

4-Quinolinecarbonitrile, 2-(Bromomethyl)- is a versatile bromomethyl-substituted quinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its bifunctional reactivity, where the bromomethyl group acts as an alkylating agent and the nitrile moiety offers a handle for further functional group transformations. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides with quinoline core structures.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of advanced organic electronic materials and metal-organic frameworks (MOFs).
• Ligand and Catalyst Development: Employed to create sophisticated chelating ligands for catalysis and metal complexation studies.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or activity-based probes for biological target identification and validation.
• Custom Synthesis and R&D: A valuable starting material for contract research organizations (CROs) and academic laboratories exploring new chemical space.

Basic Information

Product Name	4-Quinolinecarbonitrile, 2-(Bromomethyl)-
CAS No.	863654-36-8
Molecular Formula	C11H7BrN2
Molecular Weight	247.09 g/mol
Synonyms	2-(Bromomethyl)-4-quinolinecarbonitrile; 2-(Bromomethyl)quinoline-4-carbonitrile; 4-Cyano-2-(bromomethyl)quinoline; Quinoline-4-carbonitrile, 2-(bromomethyl)-; 863654-36-8; 2-Bromomethyl-4-cyanoquinoline
EINECS	Contact for details

Quality Control

Our 4-Quinolinecarbonitrile, 2-(Bromomethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our commitment to quality assurance ensures reliable performance in your most sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling under subdued light is recommended for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.