Description

8-(Aminomethyl)-1,4-Dioxaspiro[4.5]Decan-8-Ol (Wx191638) is a versatile and highly functionalized spirocyclic compound featuring both amino and hydroxyl groups, making it a valuable chiral building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, high-value molecules, particularly in the pharmaceutical sector where its unique structure enables the construction of specific stereocenters. Pharmaceutical R&D teams and fine chemical manufacturers need this high-purity intermediate for the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Bioactive Molecules: The aminomethyl and hydroxyl functionalities make it suitable for constructing peptide analogs and other bioactive scaffolds.
• Material Science Research: Potential building block for specialty polymers and functional materials requiring specific molecular architectures.
• Academic and Industrial R&D: A valuable compound for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	8-(Aminomethyl)-1,4-Dioxaspiro[4.5]Decan-8-Ol (Wx191638)
CAS No.	863565-85-9
Molecular Formula	C10H19NO3
Molecular Weight	201.26 g/mol
Synonyms	8-(Aminomethyl)-1,4-dioxaspiro[4.5]decan-8-ol; 1,4-Dioxaspiro[4.5]decan-8-ol, 8-(aminomethyl)-; 8-(Aminomethyl)-8-hydroxy-1,4-dioxaspiro[4.5]decane; 8-Hydroxy-8-(aminomethyl)-1,4-dioxaspiro[4.5]decane; WX-191638; Wx191638; Aminomethyl dioxaspirodecanol; Spirocyclic amino alcohol intermediate.
EINECS	Contact for details

Quality Control

Our 8-(Aminomethyl)-1,4-Dioxaspiro[4.5]Decan-8-Ol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for pharmaceutical R&D. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as assay, enantiomeric excess (if applicable), and impurity profiles. We adhere to cGMP principles where required, and our quality commitment ensures the material is fit for your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.