Description

7-Chloro-2-(4-Isobutylphenyl)-8-Methylquinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex quinoline-carboxylic acid structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of new drug candidates, especially those targeting inflammatory pathways.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural moiety for developing proprietary APIs with potential anti-inflammatory or analgesic properties.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes within R&D laboratories.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to create complex, high-value specialty chemicals.
• Reference Standard: Supplied as a certified reference material for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	7-Chloro-2-(4-Isobutylphenyl)-8-Methylquinoline-4-Carboxylic Acid
CAS No.	863182-57-4
Molecular Formula	C21H20ClNO2
Molecular Weight	353.84 g/mol
Synonyms	7-Chloro-2-(4-isobutylphenyl)-8-methyl-4-quinolinecarboxylic acid; 2-(4-Isobutylphenyl)-7-chloro-8-methylquinoline-4-carboxylic acid; 863182-57-4; UNII-9K2K303W8S; 9K2K303W8S; SCHEMBL23342227; DTXSID60622376; BDBM50388857
EINECS	Contact for details

Quality Control

Every batch of 7-Chloro-2-(4-Isobutylphenyl)-8-Methylquinoline-4-Carboxylic Acid is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.