Description

1-Bromo-3-Iodo-5-Nitrobenzene is a high-purity halogenated nitroaromatic compound, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring bromine, iodine, and nitro substituents, makes it an essential precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the development of functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides where the nitro and halogen groups contribute to biological activity.
• Material Science Precursor: Employed in the creation of organic semiconductors, liquid crystals, and photoactive materials due to its electron-withdrawing nitro group and halogen atoms.
• Cross-Coupling Reactions: Serves as a superior substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions, leveraging both the bromine and iodine atoms for sequential functionalization.
• Chemical Synthesis Building Block: Utilized in nucleophilic aromatic substitution and reduction reactions to create a diverse array of aniline and benzene derivatives.

Basic Information

Product Name	1-Bromo-3-Iodo-5-Nitrobenzene
CAS No.	861601-15-2
Molecular Formula	C6H3BrINO2
Molecular Weight	327.90 g/mol
Synonyms	3-Bromo-1-Iodo-5-Nitrobenzene; 5-Nitro-1,3-Dibromobenzene (Note: Incorrect but common misnomer); 1,3-Dihalo-5-nitrobenzene; Benzene, 1-bromo-3-iodo-5-nitro-; NSC Number (Contact for details); Halogenated Nitrobenzene Derivative; Building Block 861601-15-2
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Iodo-5-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials. Due to its light-sensitive nature and oxidizer properties, the recommended storage temperature is between 2°C and 8°C for long-term stability. Keep container tightly sealed in a desiccated environment to prevent moisture uptake and decomposition.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.