Description

2-(4-Nitrophenyl)-3-(Perfluorophenyl)-1-Tosylaziridine CAS NO 861437-22-1 is a specialized, high-value aziridine derivative featuring both nitro and perfluorophenyl functional groups. This compound is a critical synthetic intermediate, prized for its unique reactivity profile that enables the construction of complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for applications in medicinal chemistry and specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition or requiring fluorinated motifs for enhanced metabolic stability.
• Agrochemical Research: Used in the development of new active ingredients, where the aziridine ring and fluorinated aromatic system can contribute to unique biological activity and environmental persistence profiles.
• Advanced Material Synthesis: Employed in the creation of specialty polymers and functionalized surfaces, where the perfluorophenyl group imparts desirable properties like hydrophobicity and chemical resistance.
• Ligand and Catalyst Development: Acts as a precursor for nitrogen-containing ligands used in asymmetric catalysis and transition metal complexes.
• Academic & R&D Laboratories: Utilized in fundamental organic chemistry research to study ring-opening reactions and develop new synthetic methodologies involving strained heterocycles.

Basic Information

Product Name	2-(4-Nitrophenyl)-3-(Perfluorophenyl)-1-Tosylaziridine
CAS No.	861437-22-1
Molecular Formula	C21H13F5N2O4S
Molecular Weight	484.40 g/mol
Synonyms	1-[(4-Methylphenyl)sulfonyl]-2-(4-nitrophenyl)-3-(pentafluorophenyl)aziridine; N-Tosyl-2-(4-nitrophenyl)-3-(perfluorophenyl)aziridine; 2-(4-Nitrophenyl)-3-(pentafluorophenyl)-1-tosylaziridine; Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-(4-nitrophenyl)-3-(2,3,4,5,6-pentafluorophenyl)-; 1-Tosyl-2-(4-nitrophenyl)-3-(perfluorophenyl)aziridine
EINECS	Contact for details

Quality Control

We supply 2-(4-Nitrophenyl)-3-(Perfluorophenyl)-1-Tosylaziridine in high-purity grades suitable for research and development. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation, to ensure batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.