Description

2-(4-Methoxyphenyl)-3-(Perfluorophenyl)-1-Tosylaziridine CAS NO 861437-21-0 is a specialized, high-value aziridine derivative featuring a unique combination of methoxyphenyl, perfluorophenyl, and tosyl protecting groups. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile synthetic building block for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring precise stereochemistry and functional group manipulation.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Building block for developing new-generation herbicides and pesticides with enhanced efficacy and environmental profiles.
• Ligand & Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and organometallic complexes.
• Polymer & Material Science: Monomer or cross-linking agent for creating specialty polymers with fluorinated segments, imparting unique surface properties and chemical resistance.
• Academic & Industrial Research: Valuable reagent for methodological studies in organic synthesis, including ring-opening reactions and nucleophilic substitutions.
• Fluorinated Compound Library: Essential component for constructing diverse compound libraries in medicinal chemistry for high-throughput screening (HTS).

Basic Information

Product Name	2-(4-Methoxyphenyl)-3-(Perfluorophenyl)-1-Tosylaziridine
CAS No.	861437-21-0
Molecular Formula	C22H16F5NO3S
Molecular Weight	469.43 g/mol
Synonyms	1-[(4-Methylphenyl)sulfonyl]-2-(4-methoxyphenyl)-3-(pentafluorophenyl)aziridine; N-Tosyl-2-(4-methoxyphenyl)-3-(perfluorophenyl)aziridine; 2-(4-Methoxyphenyl)-3-(pentafluorophenyl)-1-tosylaziridine; Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-(4-methoxyphenyl)-3-(pentafluorophenyl)-; Tosyl Aziridine Derivative 861437-21-0; Pentafluorophenyl Tosylaziridine Methoxy Derivative
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Methoxyphenyl)-3-(Perfluorophenyl)-1-Tosylaziridine is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our quality commitment aligns with cGMP and ISO 9001 principles where applicable. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider using desiccants and storing under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.