Description

2-(Perfluorophenyl)-3-p-Tolyl-1-Tosylaziridine CAS NO 861437-20-9 is a specialized fluorinated aziridine derivative, a high-value building block in advanced organic synthesis. This compound matters for its unique trifunctional structure, incorporating perfluoroaryl, tolyl, and tosyl protecting groups, which enables precise stereochemical control and the introduction of fluorine atoms into complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and materials with tailored properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Research: Used in the synthesis of novel fluorinated pesticides and herbicides, leveraging fluorine's effects on biological activity and environmental persistence.
• Material Science: Building block for specialty polymers, liquid crystals, or advanced coatings where fluorine content imparts specific chemical resistance or surface properties.
• Organic Synthesis Tool: Serves as a versatile electrophile or strained-ring reagent in academic and industrial research for constructing nitrogen-containing heterocycles.
• Fluorine Chemistry: Essential for introducing perfluorophenyl groups into target molecules, a valuable motif in medicinal and materials chemistry.

Basic Information

Product Name	2-(Perfluorophenyl)-3-p-Tolyl-1-Tosylaziridine
CAS No.	861437-20-9
Molecular Formula	C22H16F5NO2S
Molecular Weight	453.42 g/mol
Synonyms	1-(4-Methylbenzenesulfonyl)-2-(perfluorophenyl)-3-(p-tolyl)aziridine; 2-(Pentafluorophenyl)-3-(4-methylphenyl)-1-[(4-methylphenyl)sulfonyl]aziridine; N-Tosyl-2-(perfluorophenyl)-3-p-tolylaziridine; Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-(perfluorophenyl)-3-(4-methylphenyl)-; 2-(Perfluorophenyl)-3-(4-methylphenyl)-1-tosylaziridine
EINECS	Contact for details

Quality Control

Our 2-(Perfluorophenyl)-3-p-Tolyl-1-Tosylaziridine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.