Description

5-(2-Thienylsulfonyl)-8-(Trifluoromethyl)-1,2,3,3A,4,5-Hexahydropyrrolo[1,2-A]Quinoxaline CAS NO 861207-20-7 is a sophisticated heterocyclic organic compound featuring a fused pyrroloquinoxaline core modified with a thienylsulfonyl group and a trifluoromethyl substituent. This compound matters as a high-value pharmaceutical intermediate and key building block in medicinal chemistry, enabling the synthesis of novel bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents, kinase inhibitors, and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Biology Probe: Used in the development of molecular probes to study enzyme function and biological mechanisms.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the unique pyrroloquinoxaline moiety.
• Agrochemical Research: Potential application as an intermediate in the development of new active ingredients for crop protection.
• Material Science: Exploration of its use in the synthesis of advanced organic electronic materials due to its fused heterocyclic structure.

Basic Information

Product Name	5-(2-Thienylsulfonyl)-8-(Trifluoromethyl)-1,2,3,3A,4,5-Hexahydropyrrolo[1,2-A]Quinoxaline
CAS No.	861207-20-7
Molecular Formula	C16H15F3N2O2S2
Molecular Weight	388.43 g/mol
Synonyms	8-(Trifluoromethyl)-5-(2-thienylsulfonyl)-1,2,3,3a,4,5-hexahydropyrrolo[1,2-a]quinoxaline; 5-(Thiophen-2-ylsulfonyl)-8-(trifluoromethyl)-1,2,3,3a,4,5-hexahydro-pyrrolo[1,2-a]quinoxaline; Pyrrolo[1,2-a]quinoxaline, 1,2,3,3a,4,5-hexahydro-8-(trifluoromethyl)-5-(2-thienylsulfonyl)-; 861207-20-7; 5-(2-Thienylsulfonyl)-8-(trifluoromethyl)hexahydropyrrolo[1,2-a]quinoxaline
EINECS	Contact for details

Quality Control

Our 5-(2-Thienylsulfonyl)-8-(Trifluoromethyl)-1,2,3,3A,4,5-Hexahydropyrrolo[1,2-A]Quinoxaline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) detailing purity, impurity profiles, and other critical parameters. Our quality commitment aligns with standards expected for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.