Description

2-[3-(Methylamino)Propyl]-1H-Isoindole-1,3(2H)-Dione, Hcl Salt is a high-purity chemical building block and intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators where its structural motif imparts specific biological activity.
• Organic Synthesis Reagent: Acts as a versatile intermediate for introducing the N-methylaminopropylphthalimide moiety into more complex molecular architectures.
• Bioconjugation & Linker Chemistry: Potential use in creating cleavable linkers for drug delivery systems or bioconjugates due to its amine functionality and phthalimide group.
• Material Science Precursor: Can be utilized in the synthesis of specialty polymers or functionalized surfaces that require specific amine-based interactions.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function or cellular processes.

Basic Information

Product Name	2-[3-(Methylamino)Propyl]-1H-Isoindole-1,3(2H)-Dione, Hcl Salt
CAS No.	861018-76-0
Molecular Formula	C12H15N2O2·HCl
Molecular Weight	254.72 g/mol
Synonyms	N-[3-(Methylamino)propyl]phthalimide hydrochloride; 1H-Isoindole-1,3(2H)-dione, 2-[3-(methylamino)propyl]-, hydrochloride; 3-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-methylpropan-1-amine hydrochloride; N-Methyl-3-phthalimidopropylamine hydrochloride; Phthalimide, N-(3-(methylamino)propyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-[3-(Methylamino)Propyl]-1H-Isoindole-1,3(2H)-Dione, Hcl Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.