Description

5-(Methylsulfonyl)-7-(Trifluoromethyl)-1,2,3,3A,4,5-Hexahydropyrrolo[1,2-A]Quinoxaline CAS NO 860785-71-3 is a high-value, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating a trifluoromethyl group and a methylsulfonyl moiety. This compound is critical for medicinal chemistry research and development, offering a sophisticated scaffold for creating novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of next-generation therapeutics targeting central nervous system (CNS) disorders, oncology, and other specialized disease areas.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization due to its unique fused ring system and functional groups.
• CNS Drug Development: Employed in the research and synthesis of potential therapeutics for neurological and psychiatric conditions.
• Oncological Agent Synthesis: Acts as a precursor in the development of targeted cancer therapies.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for creating complex, high-value molecules in contract research and manufacturing (CRAM) organizations.
• Biochemical Tool Compound: May be used in biochemical assays and as a probe to study specific biological pathways and protein interactions.

Basic Information

Product Name	5-(Methylsulfonyl)-7-(Trifluoromethyl)-1,2,3,3A,4,5-Hexahydropyrrolo[1,2-A]Quinoxaline
CAS No.	860785-71-3
Molecular Formula	C₁₃H₁₃F₃N₂O₂S
Molecular Weight	318.32 g/mol
Synonyms	5-(Methylsulfonyl)-7-(trifluoromethyl)-1,2,3,3a,4,5-hexahydropyrrolo[1,2-a]quinoxaline; 7-(Trifluoromethyl)-5-(methylsulfonyl)-1,2,3,3a,4,5-hexahydro-pyrrolo[1,2-a]quinoxaline; Pyrrolo[1,2-a]quinoxaline, 1,2,3,3a,4,5-hexahydro-5-(methylsulfonyl)-7-(trifluoromethyl)-; 860785-71-3; 5-Methanesulfonyl-7-trifluoromethyl-1,2,3,3a,4,5-hexahydropyrrolo[1,2-a]quinoxaline
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Quality Control

We maintain stringent quality control protocols for this advanced intermediate, ensuring batch-to-batch consistency and high purity suitable for research and development applications. Our quality assurance includes comprehensive analytical characterization using techniques such as HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.