Description

2,6-Piperazinedione, 4-Nitro- is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its reactive nitro and diketopiperazine functional groups.
• Peptidomimetic Chemistry: Acts as a constrained scaffold or a conformationally restricted dipeptide surrogate in the design of bioactive peptides and protease inhibitors.
• Material Science: Employed in the synthesis of specialty polymers and functional organic materials that require specific heterocyclic motifs.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic and medicinal chemistry.
• Custom Synthesis: A valuable starting material for custom manufacturing organizations (CMOs) producing bespoke compounds for client-specific projects.

Basic Information

Product Name	2,6-Piperazinedione, 4-Nitro-
CAS No.	860765-20-4
Molecular Formula	C4H5N3O4
Molecular Weight	159.10 g/mol
Synonyms	4-Nitro-2,6-piperazinedione; 4-Nitropiperazine-2,6-dione; 1,4-Diaza-5-nitrobicyclo[4.2.0]octane-2,8-dione; 4-Nitro-2,6-diketopiperazine; 4-Nitro-DKP; 4-Nitro-2,6-dioxopiperazine; 4-Nitropiperazine-2,6-diketone; 4-Nitro-1,4-diazacyclohexane-2,6-dione
EINECS	Contact for details

Quality Control

Our 2,6-Piperazinedione, 4-Nitro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.