Description

4-Chloro-2-Ethynyl-1-Nitro-Benzene is a high-purity, multi-functional aromatic building block characterized by its reactive ethynyl and nitro substituents. This compound is essential for advanced organic synthesis, enabling the construction of complex molecular architectures through cross-coupling and cycloaddition reactions. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for targeted therapies.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Serves as a monomer or cross-linking agent for creating specialized polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed in Sonogashira, Huisgen cycloaddition, and other palladium-catalyzed coupling reactions to introduce functionalized aryl groups.
• Dye & Pigment Intermediate: Acts as a building block for synthesizing complex chromophores and specialty colorants.
• Academic & Contract Research: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	4-Chloro-2-Ethynyl-1-Nitro-Benzene
CAS No.	860687-65-6
Molecular Formula	C8H4ClNO2
Molecular Weight	181.57 g/mol
Synonyms	1-Chloro-4-ethynyl-2-nitrobenzene; 2-Nitro-4-chlorophenylacetylene; 4-Chloro-2-nitrophenylacetylene; 4-Chloro-1-nitro-2-ethynylbenzene; Benzene, 4-chloro-2-ethynyl-1-nitro-; 860687-65-6; 4-Chloro-2-ethynylnitrobenzene
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2-Ethynyl-1-Nitro-Benzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity requirements for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to the light-sensitive nature of the compound, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.