Description

Ethyl 3-Chloroimidazo[1,2-A]Pyrimidine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This heterocyclic compound serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is essential for R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new compounds with enhanced biological activity.

Application

This specialized intermediate is designed for sophisticated synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides that require specific heterocyclic scaffolds for efficacy.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold for constructing compound libraries used in high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Material Science Research: Investigated as a potential monomer or precursor for creating organic electronic materials and specialty polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process scale-up for client projects.

Basic Information

Product Name	Ethyl 3-Chloroimidazo[1,2-A]Pyrimidine-2-Carboxylate
CAS No.	860612-52-8
Molecular Formula	C9H8ClN3O2
Molecular Weight	225.63 g/mol
Synonyms	Ethyl 3-chloroimidazo[1,2-a]pyrimidine-2-carboxylate; 3-Chloroimidazo[1,2-a]pyrimidine-2-carboxylic acid ethyl ester; Imidazo[1,2-a]pyrimidine-2-carboxylic acid, 3-chloro-, ethyl ester; 860612-52-8; Ethyl 3-chloroimidazo[1,2-a]pyrimidine-2-carboxylate; 2-Carbethoxy-3-chloroimidazo[1,2-a]pyrimidine
EINECS	Contact for details

Quality Control

Our Ethyl 3-Chloroimidazo[1,2-A]Pyrimidine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.