Description

2-Amino-3-Hydroxy-3-Phenylpropanoic Acid Hydrochloride is a high-purity, non-proteinogenic amino acid derivative, specifically the hydrochloride salt of L-Phenylserine. This compound is a crucial chiral building block and intermediate in advanced organic synthesis. It is primarily utilized by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of β-lactam antibiotics, protease inhibitors, and other therapeutic agents.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate the unique phenylserine moiety, modifying peptide stability and bioactivity.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzyme inhibition research.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to construct complex stereocenters.
• Agrochemical Development: Potential intermediate in the research and synthesis of advanced herbicides and plant growth regulators.

Basic Information

Product Name	2-Amino-3-Hydroxy-3-Phenylpropanoic Acid Hydrochloride
CAS No.	860252-29-5
Molecular Formula	C9H12ClNO3
Molecular Weight	217.65 g/mol
Synonyms	L-Phenylserine Hydrochloride; (2S,3R)-2-Amino-3-hydroxy-3-phenylpropanoic acid hydrochloride; β-Hydroxy-L-phenylalanine hydrochloride; (S)-2-Amino-3-hydroxy-3-phenylpropionic acid HCl; 3-Phenyl-L-serine hydrochloride; 860252-29-5; (2S,3R)-3-Phenylserine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Hydroxy-3-Phenylpropanoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.