Description

3-Bromo-6-Chloroquinoline-8-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its precise molecular architecture, which enables the construction of complex pharmacophores and functional materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Development: Used to construct advanced active ingredients for crop protection products, leveraging its halogenated quinoline core.
• Material Science Research: Serves as a building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Industrial R&D: Employed in discovery chemistry for exploring new chemical spaces and reaction methodologies.

Basic Information

Product Name	3-Bromo-6-Chloroquinoline-8-Carboxylic Acid
CAS No.	860206-90-2
Molecular Formula	C10H5BrClNO2
Molecular Weight	286.51 g/mol
Synonyms	8-Quinolinecarboxylic acid, 3-bromo-6-chloro-; 3-Bromo-6-chloro-8-quinolinecarboxylic acid; 3-Bromo-6-chloroquinoline-8-carboxylic acid; 860206-90-2; 6-Chloro-3-bromoquinoline-8-carboxylic acid; 3-Br-6-Cl-quinoline-8-COOH; Quinoline-8-carboxylic acid, 3-bromo-6-chloro- derivative
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-6-Chloroquinoline-8-Carboxylic Acid is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, supported by comprehensive analytical documentation. A detailed Certificate of Analysis (COA) providing results for identity, purity, and impurity profiles is supplied with each shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.