Description

5-Iodoquinazolin-4(3H)-One is a high-purity, halogenated quinazolinone derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceutical agents and bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other targeted small-molecule drug candidates.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study enzyme function and cellular pathways.
• Agrochemical Development: Potential intermediate in the research and synthesis of new crop protection agents.
• Academic Research: Employed in universities and research institutes for methodological development in heterocyclic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	5-Iodoquinazolin-4(3H)-One
CAS No.	860193-45-9
Molecular Formula	C8H5IN2O
Molecular Weight	272.04 g/mol
Synonyms	5-Iodo-4(3H)-quinazolinone; 5-Iodoquinazolin-4-ol; 4-Hydroxy-5-iodoquinazoline; 5-Iodo-3,4-dihydro-4-oxoquinazoline; 5-Iodo-4-quinazolinol; 860193-45-9; 5-Iodo-4(1H)-quinazolinone; 5-Iodo-4-hydroxyquinazoline
EINECS	Contact for details

Quality Control

Our 5-Iodoquinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.