Description

8-Chloro-6-Methylquinazolin-4(3H)-One is a high-purity quinazolinone derivative, a crucial heterocyclic building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides and fungicides with novel modes of action.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating tool compounds to study biological pathways and protein function.
• Material Science: A building block for advanced organic electronic materials and liquid crystals.
• Academic & Contract Research: Essential for medicinal chemistry programs and discovery research in academic and CRO settings.
• Custom Synthesis: A starting point for the bespoke manufacture of complex molecules for client-specific projects.

Basic Information

Item	Detail
Product Name	8-Chloro-6-Methylquinazolin-4(3H)-One
CAS No.	860193-22-2
Molecular Formula	C9H7ClN2O
Molecular Weight	194.62 g/mol
Synonyms	8-Chloro-6-methyl-3,4-dihydroquinazolin-4-one; 8-Chloro-6-methyl-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 8-chloro-6-methyl-; 860193-22-2; 8-Chloro-6-methylquinazolin-4-ol; 6-Methyl-8-chloroquinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our 8-Chloro-6-Methylquinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our quality commitment supports applications requiring high standards, from early-stage research to scale-up development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.