Description

5,7-Dibromoquinazolin-4(3H)-One is a high-purity, halogenated quinazolinone derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceutical agents and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating targeted molecules with specific biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the biological activity of the quinazolinone core.
• Material Science: Serves as a building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) components, due to its brominated, electron-deficient structure.
• Chemical Biology Probe Development: Utilized in creating tool compounds for studying enzyme function and cellular signaling pathways.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring functionalized quinazolinones.

Basic Information

Product Name	5,7-Dibromoquinazolin-4(3H)-One
CAS No.	860192-99-0
Molecular Formula	C8H4Br2N2O
Molecular Weight	303.94 g/mol
Synonyms	5,7-Dibromo-3,4-dihydro-4-oxoquinazoline; 5,7-Dibromo-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 5,7-dibromo-; 5,7-Dibromoquinazolin-4-ol; 5,7-Dibromo-4-hydroxyquinazoline; DBQO; 860192-99-0
EINECS	Contact for details

Quality Control

Our 5,7-Dibromoquinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.