Description

8-Bromoacetylquinoline is a versatile brominated quinoline derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its reactive bromoacetyl group makes it a valuable building block for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobial, anticancer, and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the quinoline scaffold for biological activity.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to the electron-accepting properties of the bromoacetyl group.
• Fluorescent Probe Development: Utilized in the design and synthesis of quinoline-based fluorescent dyes and sensors for biological imaging and chemical detection.
• Cross-Coupling Reactions: An important substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form more complex biaryl and conjugated systems.

Basic Information

Product Name	8-Bromoacetylquinoline
CAS No.	860113-88-8
Molecular Formula	C11H8BrNO
Molecular Weight	250.09 g/mol
Synonyms	1-(8-Quinolyl)-2-bromoethanone; 2-Bromo-1-(quinolin-8-yl)ethan-1-one; 8-Acetylquinoline bromide; 8-Quinolinyl bromomethyl ketone; 8-Bromoacetyl quinoline; Bromo(8-quinolyl)methanone; Ethanone, 2-bromo-1-(8-quinolinyl)-; 8-Bromoacetyquinoline
EINECS	Contact for details

Quality Control

Our 8-Bromoacetylquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to reliable supply and batch-to-batch consistency supports your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.