Description

(1R,2R)-N,N'-Dihydroxy-N,N'-Bis(3,3,3-Triphenylpropionyl)Cyclohexane-1,2-Diamine is a sophisticated chiral ligand and catalyst precursor of significant interest in advanced organic synthesis. Its core value lies in its ability to impart high enantioselectivity in asymmetric transformations, a critical factor for producing optically pure intermediates in pharmaceutical and fine chemical manufacturing. This compound is essential for research chemists and process development scientists working in asymmetric catalysis, particularly for the synthesis of chiral amines, amino alcohols, and other high-value building blocks.

Application

• As a chiral ligand for asymmetric hydrogenation and transfer hydrogenation reactions.
• As a catalyst precursor in the enantioselective synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• For the preparation of chiral auxiliaries used in complex natural product synthesis.
• In academic and industrial R&D for developing new asymmetric catalytic methodologies.
• As a key component in catalyst systems for producing enantiomerically pure agrochemicals and flavors/fragrances.
• For the kinetic resolution of racemic mixtures to obtain single enantiomers.

Basic Information

Product Name	(1R,2R)-N,N'-Dihydroxy-N,N'-Bis(3,3,3-Triphenylpropionyl)Cyclohexane-1,2-Diamine
CAS No.	860036-29-9
Molecular Formula	C50H48N2O4
Molecular Weight	740.93 g/mol
Synonyms	(1R,2R)-(-)-1,2-Bis[(3,3,3-Triphenylpropanoyl)amino]cyclohexane; (1R,2R)-N,N'-Bis(3,3,3-Triphenyl-1-oxopropyl)-1,2-cyclohexanediamine; (1R,2R)-Cyclohexane-1,2-diamine, N,N'-bis(3,3,3-triphenyl-1-oxopropyl)-; (1R,2R)-1,2-Diaminocyclohexane-N,N'-bis(3,3,3-triphenylpropionamide); (R,R)-Teth-DTBM; Teth-DTBM ligand; Chiral DTBM ligand; Asymmetric hydrogenation ligand 860036-29-9.
EINECS	Contact for details

Quality Control

Our production of (1R,2R)-N,N'-Dihydroxy-N,N'-Bis(3,3,3-Triphenylpropionyl)Cyclohexane-1,2-Diamine adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity, critical for catalytic performance. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing purity, enantiomeric excess (ee), and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment and opened under dry, inert conditions when necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.