Description

4-(8-Chloro-2-Cyano-5,6-Dihydro-11H-Benzo[5,6]Cyclohepta[1,2-B]Pyridin-11-Ylidene)-1-Piperidinecarboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel therapeutic agents, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily needed by pharmaceutical R&D laboratories and fine chemical producers engaged in developing new drug candidates, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Oncology Candidate Synthesis: Serves as a core scaffold for developing potential kinase inhibitors and other targeted cancer therapies.
• CNS Drug Development: Employed in the synthesis of compounds targeting neurological disorders.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for advanced organic chemistry and pharmacology studies.
• Process Chemistry: Used in scaling up synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	4-(8-Chloro-2-Cyano-5,6-Dihydro-11H-Benzo[5,6]Cyclohepta[1,2-B]Pyridin-11-Ylidene)-1-Piperidinecarboxylic Acid Ethyl Ester
CAS No.	860010-31-7
Molecular Formula	C23H20ClN3O2
Molecular Weight	405.88 g/mol
Synonyms	Ethyl 4-[(8-chloro-2-cyano-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)]piperidine-1-carboxylate; UNII-8V8T8QY9QN; 8V8T8QY9QN; BCPE; 4-(8-Chloro-2-cyano-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylic acid ethyl ester; 1-Piperidinecarboxylic acid, 4-[(8-chloro-2-cyano-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)]-, ethyl ester; Ethyl 4-(8-chloro-2-cyano-5,6-dihydrobenzo[5,6]cyclohepta[1,2-b]pyridin-11(11H)-ylidene)piperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 4-(8-Chloro-2-Cyano-5,6-Dihydro-11H-Benzo[5,6]Cyclohepta[1,2-B]Pyridin-11-Ylidene)-1-Piperidinecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. Our quality commitment aligns with ICH guidelines, and we support audits and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.