Description

7-Benzyl-4-Chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-amine is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydropyridopyrimidine class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of targeted therapeutic agents with high structural complexity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or a starting material for synthesizing probes to study specific biological pathways and enzyme functions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up synthesis under cGMP conditions for clinical trial material production.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	7-Benzyl-4-Chloro-5,6,7,8-Tetrahydropyrido[3,4-d]Pyrimidin-2-Amine
CAS No.	859825-79-9
Molecular Formula	C₁₆H₁₇ClN₄
Molecular Weight	300.79 g/mol
Synonyms	4-Chloro-7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-amine; 7-Benzyl-4-chloro-2-amino-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine; 859825-79-9; 4-Chloro-7-benzyl-5,6,7,8-tetrahydro-2-pyrido[3,4-d]pyrimidinamine; Benzyl-4-chloro-tetrahydropyridopyrimidinamine; Pyrido[3,4-d]pyrimidine, 4-chloro-7-benzyl-5,6,7,8-tetrahydro-2-amino-
EINECS	Contact for details

Quality Control

Our 7-Benzyl-4-Chloro-5,6,7,8-Tetrahydropyrido[3,4-d]Pyrimidin-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. For advanced applications, we can supply material that meets research-grade or cGMP-grade standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.