Description

5-Isoxazoleacetic Acid, 3-Methyl-, Hydrazide is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the isoxazole moiety's bioactivity.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics: The hydrazide functional group makes it valuable for constructing peptide analogs and enzyme inhibitors.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological processes and target validation.
• Fine Chemical Synthesis: Acts as a versatile building block for creating complex heterocycles and specialty chemicals.

Basic Information

Product Name	5-Isoxazoleacetic Acid, 3-Methyl-, Hydrazide
CAS No.	859285-24-8
Molecular Formula	C7H9N3O2
Molecular Weight	167.16 g/mol
Synonyms	3-Methyl-5-isoxazoleacetic acid hydrazide; (3-Methyl-1,2-oxazol-5-yl)acetic acid hydrazide; 5-Isoxazoleacetic acid, 3-methyl-, hydrazide; 3-Methylisoxazole-5-acetic acid hydrazide; 5-(Hydrazinecarbonylmethyl)-3-methylisoxazole; 3-Methyl-5-isoxazolylacetic acid hydrazide
EINECS	Contact for details

Quality Control

Our 5-Isoxazoleacetic Acid, 3-Methyl-, Hydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation and moisture uptake. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.