Description

(5-Fluoropyridin-2-Yl)Methanamine Dihydrochloride is a high-purity, fluorinated pyridine derivative offered as a dihydrochloride salt for enhanced stability and handling. This compound serves as a critical building block in modern synthetic chemistry, enabling the introduction of a functionalized aminomethylpyridine scaffold. It is primarily utilized by pharmaceutical research and agrochemical development teams for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the fluoropyridine moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the design of molecular probes, enzyme inhibitors, and tagged compounds for biochemical research.
• Material Science Research: Acts as a monomer or functionalization agent in the development of advanced polymers and specialty materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	(5-Fluoropyridin-2-Yl)Methanamine Dihydrochloride
CAS No.	859164-78-6
Molecular Formula	C6H8Cl2FN2
Molecular Weight	195.05 g/mol
Synonyms	2-(Aminomethyl)-5-fluoropyridine dihydrochloride; 1-(5-Fluoropyridin-2-yl)methanamine dihydrochloride; (5-Fluoro-2-pyridinyl)methanamine dihydrochloride; 5-Fluoro-2-pyridinemethanamine dihydrochloride; 2-Aminomethyl-5-fluoropyridine dihydrochloride; 5-Fluoro-2-(aminomethyl)pyridine hydrochloride (1:2); (5-Fluoro-2-pyridyl)methylamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (5-Fluoropyridin-2-Yl)Methanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring research-grade to cGMP-compliant materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.