Description

1,2,2',3',5',6'-Hexahydrospiro[Indole-3,4'-Pyran] is a complex spirocyclic organic compound featuring a fused indole and pyran ring system. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile scaffold in medicinal chemistry research. It is primarily utilized by R&D organizations and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules, particularly in the development of central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis: Versatile precursor for synthesizing novel spirocyclic and heterocyclic compounds in academic and industrial laboratories.
• CNS Drug Development: Used in research targeting neurological disorders due to the pharmacologically privileged indole and spirocyclic motifs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.

Basic Information

Item	Details
Product Name	1,2,2',3',5',6'-Hexahydrospiro[Indole-3,4'-Pyran]
CAS No.	859164-46-8
Molecular Formula	C15H17NO
Molecular Weight	227.30 g/mol
Synonyms	Spiro[indole-3,4'-pyran], 1,2,2',3',5',6'-Hexahydro-; 1,2,2',3',5',6'-Hexahydrospiro[indole-3,4'-pyran]; Hexahydrospiro[indole-3,4'-pyran]; Spiro[1H-indole-3,4'-pyran], hexahydro-; 859164-46-8; Spirocyclic indole-pyran derivative
EINECS	Contact for details

Quality Control

Our 1,2,2',3',5',6'-Hexahydrospiro[Indole-3,4'-Pyran] is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.