Description

4-[(1R)-1-(Acetylamino)Ethyl]Benzoic Acid is a high-purity chiral benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, which enable precise molecular construction for complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel chiral ligands.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents and Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used as a building block or precursor in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized chiral ligands for metal catalysis.
• Fine Chemical Synthesis: Intermediate in the multi-step synthesis of complex agrochemicals, dyes, and specialty materials.
• Academic and R&D: A valuable reference standard and research chemical for method development and studying structure-activity relationships (SAR).
• Peptidomimetics: Potential incorporation into peptide analogs to modify stability, bioavailability, or receptor binding.

Basic Information

Product Name	4-[(1R)-1-(Acetylamino)Ethyl]Benzoic Acid
CAS No.	859163-61-4
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	(R)-2-(4-Carboxyphenyl)propanamide; (R)-N-(1-(4-Carboxyphenyl)ethyl)acetamide; (R)-4-(1-Acetamidoethyl)benzoic acid; Benzoic acid, 4-[(1R)-1-(acetylamino)ethyl]-; (R)-α-Methyl-4-(acetylamino)benzenacetic acid; (1R)-1-(4-Carboxyphenyl)ethylacetamide; p-[(1R)-1-Acetamidoethyl]benzoic acid
EINECS	Contact for details

Quality Control

Our 4-[(1R)-1-(Acetylamino)Ethyl]Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.