Description

(+)-3,4,4A,5,6,10B-Hexahydro-2H-Naphtho[1,2-B][1,4]Oxazin-9-Ol, Hydrochloride is a high-purity chiral organic compound supplied as a hydrochloride salt. This compound is of significant interest as a key intermediate or building block in advanced pharmaceutical research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly those targeting neurological and psychiatric pathways.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs).
• Neurological Research: Used in the development of compounds for central nervous system (CNS) drug discovery programs.
• Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic structures in medicinal chemistry.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in API manufacturing.
• Process Chemistry: Utilized in route scouting and optimization for scalable pharmaceutical production.

Basic Information

Item	Details
Product Name	(+)-3,4,4A,5,6,10B-Hexahydro-2H-Naphtho[1,2-B][1,4]Oxazin-9-Ol, Hydrochloride
CAS No.	858517-21-2
Molecular Formula	C₁₄H₁₈ClNO₂
Molecular Weight	267.75 g/mol
Synonyms	(+)-3,4,4a,5,6,10b-Hexahydro-2H-naphth[1,2-b][1,4]oxazin-9-ol hydrochloride; (9S)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol hydrochloride; (S)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol hydrochloride; 858517-21-2; (9S)-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazine-9-ol hydrochloride
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested to ensure identity, purity, and consistency, meeting the rigorous demands of pharmaceutical development. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as chiral purity, assay, and impurity profiles. We support compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredient starting materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.