Description

2-Chloro-1-(4'-Nitro-[1,1'-Biphenyl]-4-Yl)Ethanone is a specialized organic building block featuring a biphenyl core functionalized with a nitro group and a reactive α-chloroketone moiety. This compound matters as a key synthetic intermediate, enabling the construction of complex molecular architectures for advanced material and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those with biphenyl-based scaffolds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the nitro and ketone functionalities are key for bioactivity.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialized polymers and liquid crystals.
• Organic Synthesis Building Block: The reactive α-chloroketone group is valuable for further functionalization via nucleophilic substitution or condensation reactions.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies and the creation of complex organic molecules.

Basic Information

Product Name	2-Chloro-1-(4'-Nitro-[1,1'-Biphenyl]-4-Yl)Ethanone
CAS No.	857563-22-5
Molecular Formula	C14H10ClNO3
Molecular Weight	275.69 g/mol
Synonyms	2-Chloro-1-(4'-nitrobiphenyl-4-yl)ethanone; 4'-Nitro-4-biphenylyl chloromethyl ketone; 1-(4'-Nitro-[1,1'-biphenyl]-4-yl)-2-chloroethanone; p-Nitrobiphenyl-4-yl chloromethyl ketone; 2-Chloro-1-(4'-nitro-1,1'-biphenyl-4-yl)ethan-1-one; α-Chloro-4'-nitrobiphenyl-4-yl methyl ketone; NSC 405124; BRN 0012004
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(4'-Nitro-[1,1'-Biphenyl]-4-Yl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.