Description

(R)-1,4-Diazabicyclo[3.2.1]Octane Dihydrochloride is a high-purity chiral bicyclic diamine salt, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile chiral ligand and catalyst precursor, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel, stereoselective synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Asymmetric Catalysis: Employed as a ligand or catalyst component in metal-catalyzed asymmetric reactions, such as hydrogenations and C-C bond formations.
• Chiral Auxiliary: Used to induce chirality in complex molecule synthesis for drug discovery and development programs.
• Agrochemical Research: A building block for developing novel, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or additive in the synthesis of chiral polymers and advanced functional materials.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process chemistry optimization.

Basic Information

Product Name	(R)-1,4-Diazabicyclo[3.2.1]Octane Dihydrochloride
CAS No.	857334-81-7
Molecular Formula	C6H14N2·2HCl
Molecular Weight	195.11 g/mol
Synonyms	(1R)-1,4-Diazabicyclo[3.2.1]octane Dihydrochloride; (R)-1,4-DABCO Dihydrochloride; (R)-1,4-Diazabicyclo[3.2.1]octane Hydrochloride; (R)-Tropane Dihydrochloride; (R)-1,4-Diazabicyclo[3.2.1]octane, Dihydrochloride; (R)-1,4-Diazabicyclo[3.2.1]octane, 2HCl; (R)-1,4-Diazabicyclo[3.2.1]octane Dihydrochloride Salt
EINECS	Contact for details

Quality Control

Our (R)-1,4-Diazabicyclo[3.2.1]Octane Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.