Description

3-(Morpholin-4-Ylmethyl)Benzoic Acid Hydrochloride Hydrate is a high-purity organic salt compound, primarily utilized as a key pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its value lies in its role as a versatile building block, enabling the introduction of both a benzoic acid moiety and a morpholine ring system into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly those developing new drug candidates or producing specialized chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production route of complex APIs that require a morpholine-substituted benzoic acid structure.
• Chemical Research & Development (R&D): Serves as a valuable reagent for medicinal chemists in structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and advanced materials requiring its specific functional groups.
• Bioconjugation & Linker Chemistry: The carboxylic acid group allows for conjugation to other molecules, making it useful in developing prodrugs or diagnostic agents.

Basic Information

Item	Details
Product Name	3-(Morpholin-4-Ylmethyl)Benzoic Acid Hydrochloride Hydrate
CAS No.	857283-67-1
Molecular Formula	C12H15NO3 · HCl · xH2O
Molecular Weight	257.71 (Anhydrous free base) / 294.17 (Anhydrous HCl salt)
Synonyms	3-[(Morpholin-4-yl)methyl]benzoic acid hydrochloride hydrate; Benzoic acid, 3-[(4-morpholinyl)methyl]-, hydrochloride, hydrate; 3-(Morpholinomethyl)benzoic acid HCl hydrate; 3-Morpholin-4-ylmethyl-benzoic acid hydrochloride hydrate; 4-[(3-Carboxyphenyl)methyl]morpholin-4-ium chloride hydrate; 3-(4-Morpholinylmethyl)benzoic acid hydrochloride hydrate
EINECS	Contact for details

Quality Control

Our 3-(Morpholin-4-Ylmethyl)Benzoic Acid Hydrochloride Hydrate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.