Description

3-Phenyl-Pyrrolidine Hydrochloride is a versatile chiral building block and intermediate of significant importance in modern synthetic organic chemistry. Its pyrrolidine core, substituted with a phenyl group, makes it a valuable scaffold for constructing complex molecules with potential biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials. Its utility spans from medicinal chemistry research to process development and scale-up manufacturing.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Agrochemical Research: Used as a building block for developing new pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Material Science: Acts as an intermediate in the production of specialty polymers and advanced organic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and discovery chemistry.

Basic Information

Product Name	3-Phenyl-Pyrrolidine Hydrochloride
CAS No.	857281-02-8
Molecular Formula	C10H14ClN
Molecular Weight	183.68 g/mol
Synonyms	3-Phenylpyrrolidine HCl; 3-Phenylpyrrolidine hydrochloride; Pyrrolidine, 3-phenyl-, hydrochloride (1:1); 3-Phenyl-pyrrolidinium chloride; (RS)-3-Phenylpyrrolidine hydrochloride; (±)-3-Phenylpyrrolidine hydrochloride; 857281-02-8
EINECS	Contact for details

Quality Control

Our 3-Phenyl-Pyrrolidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment supports compliance with relevant guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.