Description

2-Pyrroline-1,4-Dicarboxylic Acid, 3-Hydroxy-5-Methyl- (6Ci) is a high-purity, functionalized pyrroline derivative serving as a critical chiral building block and synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, high-quality intermediates for complex synthesis. The product is supplied under strict quality control to ensure batch-to-batch consistency for demanding applications.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of complex drug molecules, particularly for neurological and metabolic disorder targets.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators with specific stereochemistry.
• Ligand Synthesis: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics & Proline Analogs: Core structure for creating modified peptides and proline derivatives with enhanced biological stability or activity.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals for electronics and performance materials.
• Academic & R&D: Serves as a valuable reference standard and starting material in medicinal chemistry and organic synthesis research programs.

Basic Information

Product Name	2-Pyrroline-1,4-Dicarboxylic Acid, 3-Hydroxy-5-Methyl- (6Ci)
CAS No.	857207-74-0
Molecular Formula	C8H11NO5
Molecular Weight	201.18 g/mol
Synonyms	3-Hydroxy-5-methyl-2-pyrroline-1,4-dicarboxylic acid; 5-Methyl-3-hydroxy-1,4-dicarboxy-2-pyrroline; 1,4-Dicarboxy-3-hydroxy-5-methyl-2-pyrroline; (6Ci) designated pyrroline derivative; Hydroxymethyl pyrroline dicarboxylic acid; Proline derivative intermediate; Chiral pyrroline acid
EINECS	Contact for details

Quality Control

Every batch of 2-Pyrroline-1,4-Dicarboxylic Acid, 3-Hydroxy-5-Methyl- (6Ci) is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure compliance with exacting research and development standards. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.