Description

(1R,2R)-1-(6-Bromo-2-Methoxyquinolin-3-Yl)-4-(Methylamino)-2-(Naphthalen-1-Yl)-1-Phenylbutan-2-Ol is a high-purity, chiral organic compound of significant interest in advanced pharmaceutical research and development. This complex molecule serves as a critical building block or intermediate in the synthesis of novel therapeutic agents, particularly those targeting specific biological pathways. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the discovery of new drug candidates.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies in drug discovery programs.
• Chemical Biology Probe: Potential utility in the development of molecular probes for studying enzyme function or receptor interactions.
• Asymmetric Synthesis: Serves as a sophisticated intermediate in multi-step synthetic routes requiring high stereochemical control.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and validation in QC laboratories.

Basic Information

Product Name	(1R,2R)-1-(6-Bromo-2-Methoxyquinolin-3-Yl)-4-(Methylamino)-2-(Naphthalen-1-Yl)-1-Phenylbutan-2-Ol
CAS No.	857086-94-3
Molecular Formula	C31H27BrN2O2
Molecular Weight	539.47 g/mol
Synonyms	(1R,2R)-1-(6-Bromo-2-methoxy-3-quinolyl)-4-(methylamino)-2-(naphthalen-1-yl)-1-phenyl-butan-2-ol; (1R,2R)-1-(6-Bromo-2-methoxyquinolin-3-yl)-4-(methylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol; 857086-94-3; (1R,2R)-1-(6-Bromo-2-Methoxyquinolin-3-Yl)-4-(Methylamino)-2-(Naphthalen-1-Yl)-1-Phenylbutan-2-Ol; 1-(6-Bromo-2-methoxyquinolin-3-yl)-4-(methylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol, (1R,2R)-
EINECS	Contact for details

Quality Control

Our (1R,2R)-1-(6-Bromo-2-Methoxyquinolin-3-Yl)-4-(Methylamino)-2-(Naphthalen-1-Yl)-1-Phenylbutan-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by advanced chromatographic methods, to ensure it meets the stringent requirements of pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.