Description

3-((1R)-1-Aminopropyl)Phenol is a chiral phenolic amine building block of significant interest in advanced organic synthesis. Its value lies in its unique structure, which combines a stereogenic center with both phenolic and primary amine functionalities, enabling its use in the creation of complex, optically active molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications such as chiral ligand synthesis and as a precursor for active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug research.
• Chiral Ligand & Catalyst Synthesis: Serves as a precursor for developing enantioselective catalysts and ligands used in asymmetric synthesis.
• Agrochemical Research: Utilized in the development of new, optically active herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or modifier in the synthesis of specialty polymers and resins with specific optical or mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways.

Basic Information

Product Name	3-((1R)-1-Aminopropyl)Phenol
CAS No.	856758-60-6
Molecular Formula	C9H13NO
Molecular Weight	151.21 g/mol
Synonyms	(R)-3-(1-Aminopropyl)phenol; (1R)-1-(3-Hydroxyphenyl)propylamine; 3-[(1R)-1-Aminopropyl]phenol; Phenol, 3-[(1R)-1-aminopropyl]-; (R)-1-(3-Hydroxyphenyl)propan-1-amine; (R)-3-(1-Aminopropyl)phenol; 856758-60-6; (R)-3-Aminopropylphenol (common name variant)
EINECS	Contact for details

Quality Control

Our 3-((1R)-1-Aminopropyl)Phenol is produced under strict quality management protocols to ensure high chemical and optical purity, which is critical for sensitive chiral synthesis. Each batch is characterized by advanced analytical techniques including chiral HPLC to confirm enantiomeric excess (ee). A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.