Description

7-Bromomethyl-5-Nitrobenzofuran is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a reactive bromomethyl group and an electron-withdrawing nitro substituent on a benzofuran core, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the benzofuran scaffold's bioactivity.
• Material Science Precursor: Acts as a building block for organic semiconductors, liquid crystals, and fluorescent dyes due to the conjugated benzofuran system.
• Cross-Coupling Reactions: The bromomethyl group is amenable to various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) for carbon-carbon bond formation.
• Nucleophilic Substitution: The reactive benzylic bromide site allows for functionalization with a wide range of nucleophiles (amines, thiols, alkoxides).
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in high-throughput screening and medicinal chemistry programs.

Basic Information

Product Name	7-Bromomethyl-5-Nitrobenzofuran
CAS No.	856678-94-9
Molecular Formula	C9H6BrNO3
Molecular Weight	256.05 g/mol
Synonyms	5-Nitro-7-(bromomethyl)benzofuran; 7-(Bromomethyl)-5-nitro-1-benzofuran; 1-Benzofuran, 7-(bromomethyl)-5-nitro-; 5-Nitro-7-bromomethylbenzofuran; 7-Bromomethyl-5-nitrobenzofurane
EINECS	Contact for details

Quality Control

Our 7-Bromomethyl-5-Nitrobenzofuran is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and GC-MS for solvent residue analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging are performed under controlled lighting conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.