Description

2-(2-((6-Chlorohexyl)Oxy)Ethoxy)Ethan-1-Ol is a specialized bifunctional organic compound featuring a terminal chloroalkyl group and a hydroxyl-terminated polyether chain. This unique structure makes it a valuable chemical intermediate for the synthesis of more complex molecules, particularly in advanced material science and pharmaceutical development. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, polymer, and specialty chemical industries for creating functionalized polymers, prodrugs, and surface-modifying agents.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, where its reactive chloro and hydroxyl groups allow for selective conjugation.
• Polymer & Material Science: Serves as a monomer or chain extender for producing polyethers, polyesters, and polyurethanes with tailored hydrophilicity and functionality.
• Surface Modification Agent: Employed to functionalize surfaces of nanoparticles, silica, or other materials to impart specific chemical properties or improve biocompatibility.
• Crosslinking Agent: Acts as a crosslinker in the formulation of hydrogels, resins, and elastomers, contributing to network formation and material stability.
• Ligand & Chelator Synthesis: A building block for creating chelating agents, crown ether analogs, and other ligands used in catalysis or metal ion sequestration.
• Organic Synthesis Building Block: Provides a versatile spacer arm in multi-step synthetic routes for agrochemicals, dyes, and other fine chemicals.

Basic Information

Product Name	2-(2-((6-Chlorohexyl)Oxy)Ethoxy)Ethan-1-Ol
CAS No.	856372-59-3
Molecular Formula	C10H21ClO3
Molecular Weight	224.73 g/mol
Synonyms	6-Chlorohexyl 2-(2-hydroxyethoxy)ethyl ether; 2-[2-(6-Chlorohexyloxy)ethoxy]ethanol; 1-Chloro-6-(2-(2-hydroxyethoxy)ethoxy)hexane; Polyethylene glycol mono(6-chlorohexyl) ether; PEGylated 6-chloro-1-hexanol; 6-Chloro-1-hexanol ethoxylate; 2-(2-(6-Chlorohexyloxy)ethoxy)ethan-1-ol
EINECS	Contact for details

Quality Control

Our 2-(2-((6-Chlorohexyl)Oxy)Ethoxy)Ethan-1-Ol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and Karl Fischer titration to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Custom synthesis and purity grades (e.g., >95%, >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Chlorohexyl Content (GC)	Reported on COA
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.